As creative director, I work with our team and our partners to understand and communicate the future potential of biotechnologies.
Advisor: Pamela Silver
Thesis: “Biological Design Principles for Synthetic Biology”
Magna Cum Laude, with distinction in major
Postdoctoral Researcher, UCLA
Department of Molecular, Cell, and Developmental Biology
Fellow, UCLA Department of Design | Media Arts
A project bringing together synthetic biologists, designers,
artists, and social scientists to explore collaborations
between synthetic biology, art, and design.
Graduate Researcher, Harvard Medical School
Department of Systems Biology
Department of Humanities & Sciences
Visiting Instructor, "Bioissues," Spring 2015
Department of Media Design Practices
Adjunct Thesis Advisor, 2014-2015
Organized and mentored UCLA's first iGEM team.
Instructor, UCLA High School Summer Program
Lecturer, “Molecular Biotechnology for Engineers”
Co-taught with James Liao
Lecturer for Harvard Medical School science outreach lecture series.
Lectures on food, fuels, and the origin of life.
Instructor, “Synthetic Biology”
De Meyer SE, Briscoe L, Martinez-Hidalgo P, Agapakis C, Estrada de Los Santos P, Seshadri R, Reeve W, Weinstock G, O'Hara G, Howieson J, Hirsch AM. “Symbiotic Burkholderia species show diverse arrangements of nif/fix and nod genes, and lack typical high affinity cytochrome cbb3 oxidase genes.” Molecular Plant Microbe Interactions, 2016.
Angus AA, Agapakis CM, Fong S, Yerrapragada S, Estrada-de los Santos P, Yang P, Song N, Kano S, Caballero-Mellado J, de Faria SM, Dakora FD, Weinstock G, and Hirsch AM. "Plant-Associated Symbiotic Burkholderia Species Lack Hallmark Strategies Required in Mammalian Pathogenesis." PLOS ONE, 2014, 9(1), e83779.
Kaplan D, Maymon M, Agapakis CM, Lee A, Wang A, Prigge BA, Volkogon M, and Hirsch AM. “A Survey of the Microbial Community in the Rhizosphere of Two Dominant Shrubs of the Negev Desert Highlands, Zygophyllum dumosum Boiss. and Atriplex halimus, Using Cultivation-Dependent and -Independent Methods.” American Journal of Botany. 2013, 100(9).
Boyle PM, Burrill DR, Inniss MC, Agapakis CM, Deardon A, DeWerd JG, Gedeon MA, Quinn JY, Paull ML, Raman AM, Theilmann MR, Wang L, Winn JC, Medvedik O, Schellenberg K, Haynes KA, Viel A, Brenner TJ, Church GM, Shah JV, and Silver PA. "A BioBrick Compatible Strategy for Genetic Modification of Plants." Journal of Biological Engineering, 2012, 6:8.
Agapakis CM, Niederholtmeyer H, Noche RR, Lieberman TD, Megason SG, Way JC, and Silver PA.
Towards a Synthetic Chloroplast. PLoS ONE, 2011, 6(4): e18877.
Barstow B, Agapakis CM, Boyle PM, Grandl G, Silver PA, and Wintermute EH. "A synthetic system links FeFe-hydrogenases to essential E. coli sulfur metabolism." Journal of Biological Engineering, 2011, 5:7.
Agapakis CM, Ducat DC, Boyle PM, Wintermute EH, Way JC, and Silver PA.
Insulation of a Synthetic Hydrogen Metabolism Circuit in Bacteria. Journal of Biological Engineering, 2010, 4:3.
*JBE most highly accessed article of 2010
Florez JC, Sjögren M, Agapakis CM, Burtt NP, Almgren P, Lindblad U, Berglund G, Tuomi T, Gaudet D, Daly MJ, Ardlie KG, Hirschhorn JN, Altshuler D, Groop L.
Association testing of common variants in the insulin receptor substrate-1 gene (1RS1) with type 2 diabetes. Diabetologia. 2007, 50(6): 1209-17.
Hines J, Roy M, Cheng H, Agapakis CM, Taylor R, Crews CM.
Myriaporone ¾ structure- activity relationship studies define a pharmacophore targeting eukaryotic protein synthesis. Molecular BioSystems. 2006, 2: 371-9.
Florez JC, Wiltshire S, Agapakis CM, Burtt NP, de Bakker PIW, Almgren P, Boström KB, Tuomi T, Gaudet D, Daly MJ, Hirschhorn JN, McCarthy MI, Altshuler D, Groop L.
High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people. Diabetes. 2006, 55(1): 128-35.
Florez JC, Agapakis CM, Burtt NP, Sun M, Almgren P, Rastam L, Tuomi T, Gaudet D, Hudson TJ, Daly MJ, Ardlie KG, Hirschhorn JN, Groop L, Altshuler D.
Association Testing of the Protein Tyrosine Phosphatease IB Gene (PTPN1) With Type 2 Diabetes in 7,883 People. Diabetes. 2005, 54(6): 1884-9.
Videlock EJ, Chung VK, Hall JM, Hines J, Agapakis CM, Austin DJ.
Identification of a Molecular Recognition Role for the Activation Loop Phosphotyroside of the Src Tyrosine Kinase. Journal of the American Chemical Society. 2005, 127(6): 1600-1.
Agapakis CM. "Designing Synthetic Biology." ACS Synthetic Biology, 2013, DOI: 10.1021/sb4001068.
Agapakis CM and Tolaas S. "Smelling in Multiple Dimensions." Current Opinion in Chemical Biology (special issue on Aesthetics), 2012, 16(5-6): 569-575.
Agapakis CM, Boyle PM, and Silver PA. "Natural Strategies for the Spatial Optimization of Metabolism in Synthetic Biology." Nature Chemical Biology, 2012, 8(6): 527-535.
Agapakis CM and Silver PA.
Modular Electron Transfer Circuits for Synthetic Biology: Insulation of an Engineered Biohydrogen Pathway. Bioengineered Bugs, 2010, 1:6.
Agapakis CM and Silver PA.
Synthetic Biology: Exploring and Exploiting Biological Modularity Through the Design of Novel Biological Networks. Molecular BioSystems, 2009, 5: 704-13.
Walker, R., Agapakis CM, Watkin E, and Hirsch AM. (2015) Symbiotic nitrogen fixation in legumes: perspectives on the diversity and evolution of nodulation by Rhizobium and Burkholderia species. In: Biological Nitrogen Fixation, Volume 2. F.J. deBrujjn, (ed.). John Wiley & Sons.
Agapakis CM and Tolaas S. (2014) The Inside-Out Body. In A. D. Ginsberg, J. Calvert, P. Schyfter, A. Elfick, and D. Endy (Eds.), Synthetic Aesthetics: Investigating Synthetic Biology's Designs on Nature (pp. 255-266). The MIT Press.
With Sissel Tolaas
The Long-Lasting Intimacy of Strangers (May 2016) Group Show, The Luckman Gallery, Los Angeles, CA.
Opening (August 2014) Group Show with Amisha Gadani, Rita Blaik, and Megan Daalder at the Monte Vista Projects Gallery.
Dirt (May 2014) UCLA Art | Science Gallery, with Ellie Harmon.
Synthetic Aesthetics Friday Late (April 25, 2014) Victoria & Albert Museum, London.
Stripped (February - March 2014) Sam Francis Gallery, Crossroads School for Arts and Sciences.
Member of Science and Technology Advisory Council, Science Discovery Museums, Acton, MA (2015-present)
Co-chair, iGEM Art & Design Track (2014 & 2015)
PopTech Science Fellow (October 2013)
Participant, Synthetic Biology Leadership Accelerator Program (October 2012)
Peer reviewer for PLOS ONE, ACS Synthetic Biology, Sensors, IET Systems Biology, Bioengineered Bugs, PeerJ